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11 November 2019 ..:: Cancer » EU Projects ::..   Login
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 Relevant EU Projects

Acronym, title, webpage
Main objectives (synthetically)
'Mechanisms of toxicity of asbestos substitute mineral fibres: new approaches to hazard and risk assessment' -
·        Support the hazard and risk assessment of asbestos substitute fibres;
·        Examine the potential for induction of inflammatory changes, oxidative stress, immunotoxicity and genotoxicity for glass fibres, rock wool and wollastonite;
·        Obtain information on the molecular mechanisms and dose-response relationships governing the induction of the toxic effects.
'Improving environmental health research and management in newly associated states' -
·        Integrate the Slovak science sector acting in environmental health research and management into ERA;
·        Establish networks with research centres in the EU (focus on new member states) involved in Community environmental strategies for dioxins and related compounds, toxic mineral fibres, heavy metals, fungi and mycotoxins, alternative methods, BSE, allergy, age related and significant infectious diseases and cancer.
'Placental uptake and transfer of environmental chemicals relating to allergy in childhood years' -
·        Measure the extent of placental transfer and foetal uptake of xenobiotics directly with a human perfused placenta model;
·        Correlate the data with epidemiological information on the development of allergy in maternally exposed children.
'Evaluating human-health risk from low-dose and long-term PCB exposure' -
·        Evaluate health risk resulting from long-term human exposure to polychlorinated biphenyls (PCBs) and other persistent organo chlorines;
·        Examine both adults and children from a polluted and a background area with special respect to the blood levels of PCBs, and to health disorders, especially endocrine disrupting effects;
·        Measure dioxin-like compounds, PCB metabolites, heavy metals, and dioxin-like and oestrogenic activity in selected samples;
·        Examine neurodevelopmental disorders of children.
'Newborns and genotoxic exposure risks: Development and application of biomarkers of dietary exposure to genotoxic and immunotoxic chemicals and of biomarkers of early effects, using mother-child birth cohorts and biobanks’ -
·        Investigate exposure to chemicals in food and the environment and their connection with childhood cancer and immune disorders;
·        Study maternal exposure during pregnancy to carcinogenic and immunotoxic chemicals, the resulting foetal exposure and its effects on the foetus and in later childhood;
·        Evaluate relevant exposures of the fathers;
·        Produce new insights into the biological consequences;
·        Examine toxic chemicals such as polycyclic aromatic hydrocarbons, heterocyclic amines, nitrosamines, acrylamide, mycotoxins, dioxin, PCBs, and ethanol.
'Integrated assessment of health risks from environmental stressors in Europe' -
·        Support implementation of the European Environment and Health Action Plan, by providing the methods and tools that are essential to enable integrated assessment of environment and health risks;
·        Review and enhance the monitoring systems needed to support such analyses, including routine environmental and biomonitoring, and health surveillance;
·        Test and demonstrate the methodological framework, tools and data through integrated assessments of exposures and health risks in a number of specific policy areas;
·        Develop a toolbox for integrated environment and health risk assessment.
'Comet assay and cell array for fast and efficient genotoxicity testing’
(Contract negotiations ongoing)
·        Develop methods for reliable in vitro assays for use in screening chemicals for potential genotoxic and cytotoxic effects.

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